Linitis Plastica
  • 1% to 3% of gastric cancers are a result of an inherited gastric cancer predisposition syndrome
  • Histologically, gastric cancers may be classified as either diffuse type or intestinal type.
  • The intestinal type histopathology is linked to environmental factors and advanced age.
  • The diffuse type occurs in younger patients and is associated with a familial predisposition.

Because of a decrease in intestinal type gastric cancers, the overall incidence of gastric cancer has declined significantly in the past 50 years.

The incidence of diffuse gastric cancer (DGC), which is also called signet ring cell or linitis plastica, has remained stable, and by some reports may be increasing.